Published by on August 22, 2021
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Odontogenic tumors are heterogeneous group of lesions with diverse histopathological and clinical features. Ameloblastic fibro-dentinoma. The ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor. .. It is also distinguishable from ameloblastic fibro-dentinoma not only because it. Peripheral ameloblastic fibro-dentinoma (AFD) is an extremely rare benign mixed odontogenic tumor. From a review of the English-language literature, to the.

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Case Presentation A three-year-seven-month-old girl was referred to the Pediatric Dentistry Section, Department of Stomatology, National Cheng Kung University Hospital, to have a swelling and erythematous mass on the facial gingiva of the primary maxillary right central incisor evaluated.

Five months later, they went to the same clinic because the lesion became larger. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The second variant is a hamartomatous non-neoplastic lesion that appears to be able to differentiate into ameloblasitc ameloblastic fibroodontoma and mature further into a complex odontoma. Contemp Clin Dent ;3: Abstract Ameloblastic fibroma and related lesions constitute a group of lesions, ventinoma range in biologic behaviour from true neoplasms to hamartomas. Considerably more information on the AFD has to be dentinona in order to better understand the lesion, its biological behavior, risk of malignant transformation and relationship to the other AF-related lesion.

Aggressive atypical ameloblastic fibrodentinoma: Report of a case

Under general anaesthesia, the lesion was enucleated and the permanent right upper second molar tooth bud removed. Report on two new cases. Although molecular alternations are reported in different types of odontogenic tumors, their pathogenesis remains to be elucidated [ 78 ]. Mixed odontogenic tumours and odontomas. Localized reactive hyperplastic lesions in gingiva can be classified into 4 subcategories: The mesenchymal component was primitive connective tissue resembling the dental papilla of the tooth germ.


The treatment of AFO is associated with conservative surgical approach. Embryonic and other stem cells have long telomeres, which become shorter during differentiation or aging but are stabilized again in tumorigenesis [ 25 ]. The age of our patients provides further evidence that contradicts this conclusion as our patient is an extremely young child. World Health Organization classification of tumours; pp.

Occlusal radiograph revealed expansion of buccal cortical plate with few radiopaque areas in a well-defined radiolucent lesion Click here to view. While in some other cases, hyalinised area containing entrapped cells has been considered as an abortive dentine or dentinoid tissue because of its proximity to the odontogenic epithelial.

A year-old girl was referred to oral and maxillofacial surgery department with an incidental radiological finding of radiopaque mass in the posterior region of maxilla.

Ameloblastic fibro-odontoma

Juxtaepithelial hyalinization was evident in few areas. Ameloblastic fibro-odontoma amepoblastic defined by the World Health Organization as a neoplasm consisting of odontogenic ectomesenchyme resembling the dental papilla, epithelial strands and nest resembling dental lamina and enamel organ conjunction with the presence of dentine and enamel.

Int J Surg Case Rep.

A case presentation and histological comparison with ameloblastic fibrodentinoma. If this finding is correct, the mean age of the patients with ameloblastic fibroodontoma which is assumed to differentiate further from AF should have been higher than that of those with AF. Radiographs show a well-defined radiolucent area containing various amounts of radiopaque material of irregular size and form.

Peterson’s principles of oral and maxillofacial surgery. Although the mechanism of malignant transformation of AF and other related benign mixed odontogenic tumors remain unsettled, multiple surgical procedures of recurrent lesions remain one of the important factors in their malignant transformation.

Ameloblastic fibroma and related lesions: Kannan Venugopal were responsible for the manuscript preparation. The two main complaints associated with AFO are swelling and failure of tooth eruption. Occasionally, it may be associated with unerupted tooth.


Two additional pathologies, peripheral ameloblastoma and calcifying epithelial odontogenic tumor, should also be distinguished [ 4 ]. The fibrous element varies from abundantly cellular to mature collagenous tissue, and primitive dental papilla-like appearance could not be found. Odontogenic cysts and tumors. Some other reports demonstrated that a conservative enucleation is enough.

Giraddi GB, Garg V.

Ameloblastic fibro-odontoma

Report of a case. Introduction The ameloblastic fibro-odontoma AFO is a rare benign odontogenic lesion defined as a tumour with the general features of ameloblastic fibroma but that also contains enamel and dentine.

Ameloblastic fibrodentinoma, ameloblastic fibroma, odontogenic tumor. Clinically, it presents as a painless swelling of the affected area, usually the posterior portion of the maxilla or mandible.

Owing to the formation of dentine, whether a primitive osteodentin or the very rare mature tubular type of dentine, the tumor appears as a mixed radioopaque and radiolucent lesion with well-defined borders.

Ameloblastic fibrodentinoma of mandible. Conclusion Clinicians when dealing with radiopaque mass in posterior maxilla of children should keep the possibility of rare mixed odontogenic amelkblastic in mind.

Review of the literature and presentation of new cases of odontomas. J Oral Pathol Med. The WHO distinguishes odontogenic sarcoma devoid of dental vibro tissue AFS from those displaying focal evidence of dentinoid AFDS or dentinoid plus enameloid AFOSbut the WHO panel acknowledges that presence or absence of dental hard tissue in an odontogenic sarcoma is qmeloblastic no prognostic significance.

Thus, the formation of AFO might be based on enamel matrix production, which is one of the most important features of the lesion. It is usually slow developing and is usually seen in young persons with a mean age between 8 and 12 years [ 13 ].